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Vascular Endothelial Growth Factor
The biopsy shown here is from a seven-year-old female with nephrotic syndrome. Her serum Cr was increased to 0.9 mg/dl…
BK Nephritis
This biopsy is from a patient with ESRD due to polycystic kidney disease. He is s/p deceased donor renal transplant…
Endocarditis
Crescentic glomerulonephritis is most commonly an autoimmune-related glomerulonephritis (e.g. ANCA, anti-GBM disease, lupus nephritis). However, a recent case series (reference…
Amyloid Casts
The differential diagnosis of acute renal failure in patients with multiple myeloma includes light chain cast nephropathy, amyloidosis, and monoclonal…
Renal Medullary Angiitis
This 56-year-old female presented with acute kidney injury, hematuria, and mild proteinuria. All serologic studies were negative except for antineutrophil…
Warfarin
Patients with warfarin-related nephropathy present with an acute rise in serum Cr after becoming supratherapeutic on warfarin therapy (INR>3). The…
(CMV) Cytomegalovirus
The biopsy from this adult kidney transplant recipient shows features of cytomegalovirus (CMV) infection, including prominent enlargement (cytomegalo-) of tubular…
Hemoglobin
The H&E photomicrographs show acute tubular injury with eosinophilic beaded casts (arrow). Immunohistochemical stains were strongly positive hemoglobin in the…
Lymphocytic Leukemia (CLL and SLL)
This renal biopsy was taken from an 82-year-old man with acute renal failure and nephrotic range proteinuria. His past medical…
Thrombotic Microangiopathy
The image (trichrome stain) shows the characteristic arteriolar lesion of acute thrombotic microangiopathy. Note the prominent mucoid intimal edema and…
Renal Vein Obstruction
This biopsy is from a 60-year-old female, status post renal transplant 5 days prior, who was found to have mechanical…