The Kidneys and How They Work
Where are the kidneys and why do we need them? The kidneys are a pair of bean-shaped organs, each about…
NIH Lupus Nephritis Activity and Chronicity Indices
NIH Lupus Nephritis Activity and Chronicity Indices: A way to monitor response to treatment and disease progression. A semi-quantitative grading…
Introduction to Systemic Lupus Erythematosus and Clinical Diagnostic Criteria
Systemic lupus erythematosus (SLE) Systemic lupus erythematosus (SLE) is a systemic autoimmune disease which affects over 5 million people worldwide,…
Diabetes Mellitus
What is diabetes mellitus? Diabetes mellitus, or simply diabetes, is a metabolic disease that results in high blood sugar, either…
Armanni-Ebstein Lesion
Armanni-Ebstein lesion, originally described by Luciano Armanni in 1872, is characterized by vacuolization and PAS-positive glycogen accumulation within the cytoplasm…
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Arkana is a learning, teaching, innovating practice with one unifying passion: to work toward research breakthroughs that make our services unnecessary.
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Kidneys for Kids
What are the kidneys and what do they do? Your kidneys are organs shaped like beans (think kidney beans) and…
The Neuromuscular Junction
What is the dark staining structure? (Hint: note the small nerve twig associated with the structure). The neuromuscular junction (NMJ;…
Subepithelial Humps
The depicted electron micrograph shows numerous, large and irregular subepithelial deposits which protrude from the glomerular basement membrane towards…
Diagnose This!
Diagnose This 4/29/2024
What would be your leading Dx and subtype based on the Congo red image above showing deposition predominately in the…
Diagnose This 4/15/2024
Based on the image provided, what would be your leading diagnosis with C3-dominant immune-complex deposition? The light microscopic image depicts…
Diagnose This 4/1/2024
What is this finding and what is the significance in the transplant setting? The light microscopic image depicts an…
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