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acute T-cell mediated rejection
Twitter Poll

Twitter Poll (August 1, 2018)

ANSWER: A The criteria for acute T-cell mediated rejection Banff grade IA includes interstitial inflammation involving >25% of non-sclerotic cortical…

Vanessa Moreno, MD
By Vanessa Moreno, MD
Acute Tissue Injury
Twitter Poll

Twitter Poll (May 23, 2018)

True! Histologic evidence of acute tissue injury in AABMR includes 1 or more of the following: microvascular inflammation (glomerulitis and/or…

Vanessa Moreno, MD
By Vanessa Moreno, MD
Adenovirus, interstitial hemorrhage and edema
Teaching Points

Adenovirus

This allograft biopsy shows the characteristic features of adenovirus infection. There is prominent interstitial hemorrhage and edema (Fig. 1), acute…


transplant glomerulopathy, Chronic Active Antibody-Mediated Rejection
Teaching Points

Chronic Active Antibody-Mediated Rejection

A diagnosis of chronic active antibody-mediated rejection (ABMR) requires morphologic evidence of chronic tissue injury (e.g. transplant glomerulopathy), evidence of…

Acute TCMR Grade IIA
Twitter Poll

Twitter Poll (April 25, 2018)

ANSWER: C Mild to moderate intimal arteritis (v1), with or without interstitial inflammation and/or tubulitis is considered as acute TCMR…

Vanessa Moreno, MD
By Vanessa Moreno, MD
Acute T-Cell Mediated Rejection
Twitter Poll

Twitter Poll (April 11, 2018)

ANSWER: B The criteria for acute T-cell mediated rejection Banff grade IB includes interstitial inflammation involving >25% of non-sclerotic cortical…

Vanessa Moreno, MD
By Vanessa Moreno, MD

Chronic Active T Cell-Mediated Rejection, renal cortex
Teaching Points

Chronic Active T Cell-Mediated Rejection

Chronic active T cell-mediated rejection (TCMR) was included in the 2017 Banff classification system for the evaluation of kidney allografts…

Transplant Arteriopathy, active antibody-mediated rejection
Diagnose This!

Diagnose This! (March 19, 2018)

What is your diagnosis in this renal transplant biopsy? …

L. Nich Cossey, MD
By L. Nich Cossey, MD
mild endocapillary hypercellularity with rare double contour formation of the capillary loops, Proliferative Glomerulonephritis with Monoclonal IgG Deposits
Teaching Points

Proliferative Glomerulonephritis with Monoclonal IgG Deposits

This biopsy was performed on an 81-year-male, status post renal transplant, who presented with increased creatinine (2.3 mg/dl) and microscopic…


Intimal Arteritis
Twitter Poll

Twitter Poll (Febuary 28, 2018)

ANSWER: C Intimal arteritis (v1 and v2) is more commonly associated with mixed ABMR/TCMR than with pure ABMR. It may…

Vanessa Moreno, MD
By Vanessa Moreno, MD
Intimal Arteritis
Twitter Poll

Twitter Poll (February 28, 2018)

ANSWER: C Intimal arteritis (v1 and v2) is more commonly associated with mixed ABMR/TCMR than with pure ABMR. It may…

Vanessa Moreno, MD
By Vanessa Moreno, MD
BK Nephritis with Nuclear Inclusions in a Transplant on H&E
Diagnose This!

Diagnose This! (February 26, 2018)

What is your diagnosis of this renal transplant patient? …

L. Nich Cossey, MD
By L. Nich Cossey, MD

Active Antibody Mediated Rejection
Diagnose This!

Diagnose This! (February 19, 2018)

What is your diagnosis in this renal transplant patient?   …

L. Nich Cossey, MD
By L. Nich Cossey, MD
Acute Pyelonephritis
Teaching Points

Acute Pyelonephritis in Transplants

Acute pyelonephritis in the transplant setting (allograft pyelonephritis) is a known cause of allograft dysfunction and a complication that occurs…

Tubulopathy
Twitter Poll

Twitter Poll (January 11, 2018)

ANSWER D: Tubulopathy with isometric vacuolization, acute tubular injury, acute arteriolopathy and TMA can be seen in acute CNIT.

Vanessa Moreno, MD
By Vanessa Moreno, MD