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Art of Medicine: Proliferative Glomerulonephriits with Monoclonal Immunoglobulin Deposits
The above painting shows normal bone marrow, containing erythroid and myeloid precursors at various stages of maturation and normal trabeculae.…
Art of Medicine: Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits
Small destructive B cell or plasma cell clones may be responsible for disease development. The above painting shows normal bone…
Art of Medicine: Monoclonal Gammopathies of Renal Significance
Monoclonal Gammopathies of Renal Significance The above painting is of a bone marrow biopsy showing replacement of the hematopoietic elements…
Type 1 Cryoglobulinemic Glomerulonephritis
The patient is a 75 year-old female who presents with proteinuria, a necrotic skin lesion on her lower extremity, and…
Disease Week: Monoclonal Gammopathy of Renal Significance
Disease Week: Monoclonal Gammopathy of Renal Significance Summary: Renal disease caused by parenchymal deposition of circulating monoclonal immunoglobulins (mIg)…
Light Chain Cast Nephropathy
A 75-year-old female is found to have a creatinine of 4.0 mg/dL on a routine laboratory examination. At the hospital,…
Art of Medicine: Fanconi Syndrome
This painting shows the transition between a proximal tubule and the thick descending limb of the loop of Henle. The…
AL Amyloidosis
A 70 year-old female presents with nephrotic range proteinuria and a creatinine of 1.2. She was in her normal level…
Art of Medicine: Light Chain Proximal Tubulopathy
The painting above shows light chain proximal tubulopathy with crystals, which is one type of a monoclonal gammopathy of renal…
Twitter Poll (December 7, 2018)
ANSWER: D MGRS was introduced to acknowledge a clonal plasma cell or B lymphocyte proliferation causing a renal lesion in…
Diagnose This (November 12, 2018)
What is your diagnosis and what do you need to prove it? …
Diagnose This! (August 6, 2018)
What is your diagnosis? This is a complicated case. The photomicrographs show a membranoproliferative pattern glomerulonephritis (MPGN) with IgG Lambda…
Diagnose This (July 23, 2018)
What is your diagnosis? The images show thickened tubular basement membranes on PAS stain and kappa restricted staining of the…