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A Diagnostician’s Field Guide To Crystalline Nephropathies
This discussion focuses on a review article of crystals seen in renal biopsies. Crystalline nephropathies are often associated with systemic…
Twitter Poll (February 5, 2020)
ANSWER: D, All of the Above 2,8-dihydroxyadeninuria (DHA) disease is a rare autosomal recessive disorder caused by complete adenine phosphoribosyltransferase…
Renal Oxalosis
A 25-year-old female presents to the hospital with malaise and a creatinine of 3.5. She reports that she was in…
Bile Stained Calcium Oxalate Crystals
A renal biopsy was performed on this 75-year-old female who presented with acute liver failure, jaundice and acute renal failure…
2,8 DHA Crystalline Nephropathy
The renal biopsy shown here has crystals present within the tubular lumens and cytoplasm with a brownish appearance by H&E…
Oxalate Due to Vitamin C
A 51-year-old female with a history of SLE was found to have acute renal failure. There was no evidence…
Calcium Phosphate Deposits
Calcium phosphate deposits Calcium phosphate deposits within the kidney may be seen in the setting of hypercalcemia/ hypercalciuria or hyperphosphatemia/…
Diagnose This! (October 16, 2017)
What is your diagnosis? The photomicrograph shows a distended tubule with an intratubular crystalline cast with argyrophilia.…
2,8-Dihydroxyadenuria
Adenine phosphoribosyltransferase (APRT) deficiency results from an autosomal recessive enzyme defect of purine metabolism and leads to 2,8-dihydroxyadenine (2,8-DHA) crystalline…