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collapsing glomerulopathy in APOL1
Diagnose This!

Diagnose This (January 17, 2022)

This is the albumin immunofluorescence stain from a biopsy from a patient with recent COVID pneumonia and nephrotic syndrome. What…

SARS-CoV-2, COVAN, Covid-19, collapsing Myoglobin cast, renal pathology
Art of Medicine

Art of Medicine: Covid-19 Associated Nephropathy (COVAN)

Development of acute kidney injury (AKI) in the setting of COVID-19 substantially worsens outcomes, with increased morbidity and mortality, and…


MYMP, Caza and Larsen, Covid-19 research
Arkana Visualized

Another MYMP Sighting!

Another MYMP sighting! Durning our case conference today, Dr. Caza and Dr. Larsen discussed their recently published paper covering AKI…

By Kathryn Webb
APOL1 Risk Variants, Twitter Poll, renal disease, arkana laboratories
Twitter Poll

Twitter Poll (September 26, 2019)

ANSWER: C, Black APOL1-risk alleles have been reported only on African-derived chromosomes, including individuals from West Africa and recently admixed…

By Vanessa Moreno, MD
Collapsing Glomerulopathy
Art of Medicine

Art of Medicine: Collapsing Glomerulopathy

The above painting shows a glomerulus with capillary tuft collapse, visceral epithelial cell hyperplasia, and numerous protein resorption droplets within…


Lupus Nephritis Genetics
Art of Medicine

Art of Medicine: Lupus Nephritis Genetics

The above painting shows an image of a sequencing gel, which are produced by DNA synthesis in the presence of…

APOL1 gene, Arkana Laboratories, renal pathology research
Arkana Voices

APOL1: Why Is It Important?

I have been working at Arkana Laboratories (formerly Nephropath) for close to seven years as the Molecular Diagnostics Laboratory Supervisor.…

By Marjorie Beggs, PhD
Collapsing Glomerulopathy, APOL1, arkana laboratories, kidney disease, renal pathology
Twitter Poll

Twitter Poll (April 17, 2019)

ANSWER: D Collapsing glomerulopathy has been associated with certain infectious disease including HIV, Hepatitis C, HTLV-1, parvovirus B19, cytomegalovirus, tuberculosis,…

By Vanessa Moreno, MD

AAPOAI Amyloidosis
Twitter Poll

Twitter Poll (March 21, 2018)

ANSWER: B AAPOAI Amyloidosis is the 2nd most common systemic hereditary amyloidosis which can be seen in kidney, liver, larynx,…

By Vanessa Moreno, MD
Collapsing glomerular lesions
Teaching Points

Collapsing Morphology

Collapsing glomerular lesions are aptly named, given the prominent collapse of glomerular tuft capillary loops. There is also hyperplasia and…

Microcystic Tubular Dilatation
Teaching Points

Microcystic Tubular Dilatation

Microcystic dilatation of tubules is a non-specific morphologic finding associated with various diseases, including obstructive nephropathy, HIV-associated nephropathy (HIVAN), congenital…


Collapsing Glomerulopathy
By L. Nich Cossey, MD
Collapsing Glomerulopathy
Teaching Points

Collapsing Glomerulopathy

Collapsing glomerulopathy is characterized by glomerular tuft collapse with overlying epithelial hypertrophy and hyperplasia in Bowmans space. This pattern of…

Collapsing glomerulopathy
Twitter Poll

Twitter Poll (October 4, 2017)

Answer: D Collapsing glomerulopathy has been associated with infection (HIV, parvovirus B19), drugs (INFs, BPs, CNIs) and APOL1 mutation in…

By Vanessa Moreno, MD