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Collapsing Glomerulopathy

Chris Larsen, MD renal pathologist at arkana laboratories
By Chris Larsen, MD

Nov 30, 2017

Collapsing Glomerulopathy
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Collapsing glomerulopathy is characterized by glomerular tuft collapse with overlying epithelial hypertrophy and hyperplasia in Bowman’s space. This pattern of glomerular injury is most commonly seen in African Americans and has been shown to be strongly associated with the presence of APOL1-mediated kidney disease risk variants in a number of associated diseases including HIV infection, lupus nephritis, interferon therapy, PLA2R-positive membranous glomerulopathy, and idiopathic cases.


Quick note: This post is to be used for informational purposes only and does not constitute medical or health advice. Each person should consult their own doctor with respect to matters referenced. Arkana Laboratories assumes no liability for actions taken in reliance upon the information contained herein.