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fibrillary glomerulopathy
By L. Nich Cossey, MD
Chronic Uric Acid Nephropathy
Teaching Points

Chronic Uric Acid Nephropathy

Chronic uric acid nephropathy results from deposition within the renal parenchyma of monosodium urate monohydrate. While the disease may occur…

Nephrocalcinosis
By L. Nich Cossey, MD

Alport Syndrome
Teaching Points

Alport Syndrome

This biopsy from a 22-year-old Hispanic male with a history of hematuria, subnephrotic proteinuria, and chronic kidney disease shows essentially…

adenine phosphoribosyltransferase
Diagnose This!

Diagnose This! (October 16, 2017)

What is your diagnosis?       The photomicrograph shows a distended tubule with an intratubular crystalline cast with argyrophilia.…

By L. Nich Cossey, MD
Bile Cast Nephropathy
Teaching Points

Bile Cast Nephropathy

Bile cast nephropathy is one cause of acute or chronic kidney injury in patients with liver disease (especially obstructive cholestasis).…


Monoclonal Gammopathy
Teaching Points

Monoclonal Gammopathy of Renal Significance

The renal biopsy shown here has an MPGN pattern of injury by light microscopy. Routine immunofluorescence on the fresh (unfixed)…

chronic transplant arteriopathy
Teaching Points

Chronic Transplant Arteriopathy

This image shows an arterial cross-section with features of chronic transplant arteriopathy (a.k.a. sclerosing transplant vasculopathy and chronic allograft vasculopathy).…

IgG4-Related Disease
By L. Nich Cossey, MD

Sjogrens Syndrome
Teaching Points

Sjogrens

Sjgrens syndrome is an autoimmune disease involving primarily the lacrimal and salivary glands. However, up to 27% of patients will…

Fabry Disease
By L. Nich Cossey, MD
Chronic Active Tubulointerstitial Nephritis
Teaching Points

Chronic Active Tubulointerstitial Nephritis

Chronic tubulointerstitial nephritis in children may be secondary to a number of possible etiologies such as drug and other exogenous…


Malakoplakia
Teaching Points

Malakoplakia

Learn about Malakoplakia An adult patient in the mid-fifties with a deceased donor renal transplant for three years (primary disease…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD
Renal hemosiderosis
Teaching Points

Hemosiderin

Renal hemosiderosis is a rare etiology of kidney injury that occurs secondary to diseases with chronic intravascular hemolysis. The most…

Megalocytic Interstitial Nephritis
Teaching Points

Megalocytic Interstitial Nephritis

This biopsy shows a chronic active interstitial nephritis with numerous interstitial foamy macrophages containing abundant PAS-positive cytoplasmic granules (Fig 1-3).…