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(159 Results)Vascular-Limited AL Amyloidosis
A renal biopsy was performed on this 78 year old male with history of diabetes mellitus, hypertension and monoclonal gammopathy…
Twitter Poll (May 2, 2018)
ANSWER: DNAJB9 DnaJ homolog subfamily B member 9 (DNAJB9) is a novel proteomic tissue biomarker for Fibrillary glomerulonephritis (FGN) that…
LECT2 Amyloidosis
The renal biopsy from this 79-year-old Hispanic male shows extensive glomerular, tubulointerstitial and vascular deposition of a PAS-pale (Fig 1),…
FSGS Types
The 3 main FSGS Types Are there clues to help distinguish among primary, genetic, and secondary focal segmental glomerulosclerosis (FSGS)…
Diagnose This (April 16, 2018)
The immunofluorescence study is negative. What is your diagnosis? …
Twitter Poll (March 28, 2018)
ANSWER: D Some of the histologic features observed in Sickle Cell Nephropathy that involve the glomerular compartment are: enlarged glomeruli…
Membranous-Like Glomerulopathy with Masked IgG-Kappa Deposits
Immunoglobulin deposits identified on renal biopsy samples by paraffin immunofluorescence that show negative staining by routine immunofluorescence on frozen tissue…
Resolving Membranous Glomerulopathy
A renal biopsy was performed on this 55-year-old female with a history of biopsy-proven membranous glomerulopathy status post immunosuppressive therapy,…
Diagnose This (March 26, 2018)
In the setting of weak C3 (1-2+) only staining by routine immunofluorescence, what is your diagnosis? …
Pushing Glass (March 23, 2018)
These images are from the kidney biopsy of a 70-year-old woman with a history of hypertension and valvular heart disease…
Twitter Poll (March 21, 2018)
ANSWER: B AAPOAI Amyloidosis is the 2nd most common systemic hereditary amyloidosis which can be seen in kidney, liver, larynx,…
Congo Red Stain Tutorial
Congo Red Stain Tutorial: What does it show? Positive Congo red staining in tissue with apple-greenbirefringenceunderpolarized lightis diagnostic of the…
Collapsing Morphology
Collapsing glomerular lesions are aptly named, given the prominent collapse of glomerular tuft capillary loops. There is also hyperplasia and…
When Lightning Strikes Twice
This biopsy came to us for a workup on proteinuria. The patient is a 68-year-old female with a history of…