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calcineurin inhibitor toxicity
Pushing Glass

Pushing Glass (April 18, 2017)

A 45 year-old man received renal transplantation for HCV-associated end stage renal disease. He is currently treated with Sofobuvir, Tacrolimus…

By Dao-Fu Dai, MD
Antibody-Mediated Rejection
Diagnose This!

Diagnose This! (April 17, 2017)

What is this stain and what does this finding mean in a transplant patient (Hint: Its not a vascular marker).…

By L. Nich Cossey, MD
Necrotizing Vasculitis
Teaching Points

Necrotizing Vasculitis

Necrotizing vasculitis as shown using fluorescence with DAPI-FITC-Texas Red excitation on an H&E stained section. Subtle and not so subtle…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD

Podcast

The Story of IF

Brighter than the moon! Learn how immunofluorescence became a shining light in renal pathology interpretation.

Fred Silva, MD renal pathologist at arkana laboratories
By Dr. Fred Silva
Amyloid Composed of Leukocyte Chemotactic Factor 2 (LECT2)
Teaching Points

LECT2

Photomicrographs show extensive interstitial and glomerular deposition of Congo red positive material that stains positive for LECT2. Despite being one…

FedEx Staff
Arkana Visualized

FedEx

We can’t thank the people at FedEx enough! Our local FedEx staff is just as committed to our patients as…

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By Chassity Jordan

Jones Stain
Teaching Points

Jones Stain

The silver impregnation stain is a key method of identifying basement membranes in human tissue, and its application in renal…

Dr. Amin, Nephropathologists, Arkana Laboratories Doctors
Arkana Physician Spotlight

Arkana Physician Spotlight: Dr. Amin

Dr. Amin joined Arkana Laboratories in 2016 after successful completion of fellowships in cardiovascular pathology (2015) and renal pathology (2016)…

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By Chassity Jordan
Cryoglobulinemic Glomerulonephritis
Teaching Points

Cryoglobulinemic Glomerulonephritis

Figure 1: PAS-stained section showing a glomerulus with a membranoproliferative pattern of glomerular injury characterized by mesangial matrix expansion and…


AL Type (Lambda Light Chain Restricted)
By L. Nich Cossey, MD
Diffuse and Nodular Glomerulosclerosis in Diabetic Glomerulopathy
Teaching Points

Diffuse and Nodular Glomerulosclerosis in Diabetic Glomerulopathy

Diffuse and nodular glomerulosclerosis is the classic appearance of diabetic glomerulopathy. Note the variability in mesangial areas in this one…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD
UAMS KIDNEYCon
Arkana Visualized

KIDNEYcon

We’re at the UAMS KIDNEYCon today! Dr. Shree Sharma is teaching at the renal biopsy session this morning. Illustration by…

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By Chassity Jordan

Arkanines Pet photos, Arkana Laboratories
Arkanines

Arkanines: Rosie

Some days you just need a king-size bed all to yourself. That’s precisely what Rosie prefers. Rosie belongs to Merri,…

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By Chassity Jordan
Podcast

The Story of EM

In this episode, Dr. Fred Silva gives the history of the electron microscope.

Fred Silva, MD renal pathologist at arkana laboratories
By Dr. Fred Silva
THSD7A Protein
Teaching Points

THSD7A

Granular capillary loop staining for thrombospondin type-1 domain-containing 7A (THSD7A). Our understanding of the pathogenesis of membranous glomerulopathy was transformed…