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Podcast

History of Renal Biopsy

Find out how a mistake brought us the practice of renal biopsies in this episode of Throwback Thursday with Dr.…

Fred Silva, MD renal pathologist at arkana laboratories
By Dr. Fred Silva
Proliferative Glomerulonephritis with Monoclonal IgG Deposits
Teaching Points

Proliferative Glomerulonephritis with Monoclonal IgG Deposits

The glomerulus pictured for light microscopy shows membranoproliferative changes with mesangial hypercellularity, GBM duplication, and endocapillary proliferation. There is light…

Anti-GBM (Anti-Glomerular Basement Membrane)
Teaching Points

Anti-GBM

A 19-year-old Caucasian male patient presented with acute renal failure. Serum creatinine was 4.9 mg/dL and he had hematuria and…


Oxalate Nephropathy
Teaching Points

Oxalate Nephropathy

H&E stained section (Fig. 1) demonstrating acute tubular injury with frequent translucent intratubular crystalline deposits on a background of severe…

Lipoprotein Glomerulopathy
Diagnose This!

Diagnose This! (April 24, 2017)

What is the finding shown and what disease does this likely represent?   …

By L. Nich Cossey, MD
Arkanines: Truman, Arkana Laboratories
Arkanines

Arkanines: Truman

Meet Truman! He belongs to our director, Dr. Walker (and our real boss, Mrs. Gail). Truman enjoys going to daycare,…

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By Chassity Jordan

acute tubular injury with numerous pigmented myoglobin casts
Teaching Points

Myoglobin Casts

A 54-year-old man with a history of hypertension and hypercholesterolemia presented with complaints of generalized muscle stiffness and cola-colored urine.…

Podcast

APOL1

For our inaugural episode, Dr. Kenan presents an extended discussion of APOL1 gene risk variants. Article discussed: www.ncbi.nlm.nih.gov/pubmed/21997394

Dr. Daniel Kenan renal pathologist at Arkana laboratories
By Dr. Daniel Kenan
calcineurin inhibitor toxicity
Pushing Glass

Pushing Glass (April 18, 2017)

A 45 year-old man received renal transplantation for HCV-associated end stage renal disease. He is currently treated with Sofobuvir, Tacrolimus…

By Dao-Fu Dai, MD

Antibody-Mediated Rejection
Diagnose This!

Diagnose This! (April 17, 2017)

What is this stain and what does this finding mean in a transplant patient (Hint: Its not a vascular marker).…

By L. Nich Cossey, MD
Necrotizing Vasculitis
Teaching Points

Necrotizing Vasculitis

Necrotizing vasculitis as shown using fluorescence with DAPI-FITC-Texas Red excitation on an H&E stained section. Subtle and not so subtle…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD
Podcast

The Story of IF

Brighter than the moon! Learn how immunofluorescence became a shining light in renal pathology interpretation.

Fred Silva, MD renal pathologist at arkana laboratories
By Dr. Fred Silva

Amyloid Composed of Leukocyte Chemotactic Factor 2 (LECT2)
Teaching Points

LECT2

Photomicrographs show extensive interstitial and glomerular deposition of Congo red positive material that stains positive for LECT2. Despite being one…

FedEx Staff
Arkana Visualized

FedEx

We can’t thank the people at FedEx enough! Our local FedEx staff is just as committed to our patients as…

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By Chassity Jordan
Jones Stain
Teaching Points

Jones Stain

The silver impregnation stain is a key method of identifying basement membranes in human tissue, and its application in renal…