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December 7, 2017

Cholesterol Microemboli

Cholesterol emboli involving the kidney may manifest clinically as acute kidney injury, hematuria, proteinuria (both non-nephrotic and nephrotic range), and even new-onset hypertension. This biopsy illustrates a rare example of glomerular involvement (Fig. 1). Most emboli are identified “upstream” within interlobular and/or arcuate arteries (Fig. 2). Prior to this biopsy, the patient had recently undergone an arterial catheterization procedure.
Lusco MA, et al. AJKD Atlas of Renal Pathology: Cholesterol Emboli. Am J Kidney Dis. 2016 Apr; 67(4):e23-4. PMID: 27012950.