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Ask-Upmark
This kidney biopsy is from a 16-year-old boy with a history of chronic reflux nephropathy. Imaging findings showed unilateral segmental…
Diagnose This! (February 12, 2018)
What is your diagnosis? (Congo red is negative as is routine immunofluorescence) …
Fibronectin Glomerulopathy
A renal biopsy was performed in a 32-year-old female with microscopic hematuria and nephrotic range proteinuria of 4 grams per…
Fabry Disease in Female Carriers
A renal biopsy was performed on a 51-year-old female with strong family history of Fabry disease and a known carrier…
Amyloid Cast Nephropathy
Cases of light chain cast nephropathy occasionally show amyloid staining properties including positive staining for Congo red with green birefringence…
Fibrinogen Aα-chain Amyloidosis
A 65-year-old male, with no significant past medical history, presents with proteinuria and worsening renal function. The serum creatinine is…
Apolipoprotein A-IV Amyloidosis
This renal biopsy from a 71-year-old female, who presented with progressively worsening renal failure, shows unremarkable glomeruli by light microscopy…
Embryonal Hyperplasia of Bowman’s Capsule Epithelium
H&E and PAS-stained sections from the kidney of an 8-year-old male with advanced nephrosclerosis of unknown etiology. An exuberant proliferation…
Sclerosing Peritubular Nodule
Todays teaching point is a true zebra in renal pathology. The arrows in the light microscopic image identify what have…