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Apolipoprotein A-IV Amyloidosis
This renal biopsy from a 71-year-old female, who presented with progressively worsening renal failure, shows unremarkable glomeruli by light microscopy…
Anti-Brush Border Antibody Disease IF
These photomicrographs show the classic immunofluorescence staining pattern for anti-LRP2 nephropathy, a disease that leads to severe renal tubular injury…
IgG4-Related Tubulointerstitial Nephritis
IgG4-related disease is a systemic inflammatory and sclerosing disorder which may affect a wide range of different organs including the…
Calcium Phosphate Deposits
Calcium phosphate deposits Calcium phosphate deposits within the kidney may be seen in the setting of hypercalcemia/ hypercalciuria or hyperphosphatemia/…
Monoclonal Gammopathy of Renal Significance
The renal biopsy shown here has an MPGN pattern of injury by light microscopy. Routine immunofluorescence on the fresh (unfixed)…
Chronic Transplant Arteriopathy
This image shows an arterial cross-section with features of chronic transplant arteriopathy (a.k.a. sclerosing transplant vasculopathy and chronic allograft vasculopathy).…
Sjogrens
Sjgrens syndrome is an autoimmune disease involving primarily the lacrimal and salivary glands. However, up to 27% of patients will…
Chronic Active Tubulointerstitial Nephritis
Chronic tubulointerstitial nephritis in children may be secondary to a number of possible etiologies such as drug and other exogenous…
Malakoplakia
Learn about Malakoplakia An adult patient in the mid-fifties with a deceased donor renal transplant for three years (primary disease…
Hemosiderin
Renal hemosiderosis is a rare etiology of kidney injury that occurs secondary to diseases with chronic intravascular hemolysis. The most…
Megalocytic Interstitial Nephritis
This biopsy shows a chronic active interstitial nephritis with numerous interstitial foamy macrophages containing abundant PAS-positive cytoplasmic granules (Fig 1-3).…