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Case 2: A Crescentic Conundrum
The patient is a 75-year-old female with a history of hypertension who presents with acute kidney injury. Her serum creatinine…
Disintegrating Capillary Loop Riddled with Microperformations
This acellular scanning EM shows disintegrating capillary loop riddled with microperformations in a patient with crescentic glomerulonephritis. Photo credits to…
Diagnose This (January 24, 2022)
In a patient with RPGN and this morphological finding on biopsy, what is the most likely diagnosis? …
Twitter Poll (April 28, 2021)
Answer: A, Linear GBM Anti-GBM disease is classically characterized by bright linear staining with IgG by immunofluorescence. By light…
Twitter Poll (December 11, 2019)
Answer: D, All of the Above Anti-GBM disease presents with rapidly progressive glomerulonephritis (GN) with or without pulmonary hemorrhage. On…
Twitter Poll (August 22, 2018)
ANSWER: D Anti-GBM disease is a rare small vessel vasculitis that affects glomerular and pulmonary capillaries. The majority of patients…
Twitter Poll (February 21, 2018)
ANSWER: D ANCA-associated GN and anti-GBM GN are the most common causes of pulmonary-renal syndrome accounting for about 90% of…
Twitter Poll (February 1, 2018)
ANSWER: C Approximately 25-30% of the patients with anti-GBM crescentic glomerulonephritis are ANCA positive, usually for MPO-ANCA.
Twitter Poll (November 8, 2017)
ANSWER: B The characteristic immunofluorescence staining on Anti-GBM Glomerulonephritis is strong and linear IgG along glomerular basement membranes.
Anti GBM Disease
This biopsy from an 80-year-old male with acute kidney injury shows glomeruli with frequent rupture of the capillary loops and…
Anti-GBM
A 19-year-old Caucasian male patient presented with acute renal failure. Serum creatinine was 4.9 mg/dL and he had hematuria and…
Pushing Glass (March 14, 2017)
The patient is a 61-year-old female who presents with hematuria and a creatinine of 6.23 mg/dL (baseline creatinine of 1.17…
