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Fibrocellular Crescent With A Small Remnant Of The Glomerular Tuft
eyeSCANdy

Fibrocellular Crescent

This acellular scanning EM shows a fibrocellular crescent with a small remnant of the glomerular tuft (middle right). Photo credits…

acellular scanning EM image of Glomerulus with Fibrocellular Crescent
eyeSCANdy

Glomerulus with Fibrocellular Crescent

Todays #eyesSCANdy image shows acellular scanning EM of a glomerulus with fibrocellular crescent (right). Photo credits to Dr. Stephen Bonsib!

Disintegrating Capillary Loop
eyeSCANdy

Disintegrating Capillary Loop Riddled with Microperformations

This acellular scanning EM shows disintegrating capillary loop riddled with microperformations in a patient with crescentic glomerulonephritis. Photo credits to…


empty lacunar spaces
eyeSCANdy

Empty Lacunar Spaces

Todays eyeSCANdy image shows acellular scanning EM showing empty lacunar spaces of a fibrocellular crescent previously occupied by cells. Photo…

Glomerulus With Fibrocellular Crescent
eyeSCANdy

Glomerulus With Fibrocellular Crescent

Its eyeSCANdy Tuesday! This image shows acellular scanning EM showing a glomerulus with a fibrocellular crescent (top). Photo credits…

GBM Perforations in Necrotizing GN
eyeSCANdy

GBM Perforations in Necrotizing GN

This eyeSCANdy image shows acellular scanning EM with variable-sized discrete GBM perforations in segmental necrotizing and crescentic glomerulonephritis! Image courtesy…


Dysmorphic Red Blood Cells, renal pathology, eyescandy, Dr. Stephen Bonsib
eyeSCANdy

Dysmorphic Red Blood Cells

Todays eyeSCANdy image shows dysmorphic red blood cells from the urine of a patient with crescentic glomerulonephritis. Image courtesy of…

Disease Week

Disease Week: Bacterial infection-associated glomerulonephritis and endocarditis-associated glomerulonephritis

Monday Renal disease related to infective endocarditis was first reported over 100 years ago. However, the initial literature describing nephritis…

Anti-GBM in renal biopsy at Arkana Laboratories
Twitter Poll

Twitter Poll (August 22, 2018)

ANSWER: D Anti-GBM disease is a rare small vessel vasculitis that affects glomerular and pulmonary capillaries. The majority of patients…

Vanessa Moreno, MD
By Vanessa Moreno, MD

ANCA Disease, LECT2 Amyloid, IgG4-Related Disease, AL amyloidosis, ANCA, digging deeper, Dr. Messias, Arkana Laboratories, pathology diseases
Digging Deeper

Digging Deeper, Literally

This biopsy came from a 79-year-old patient. He had presented with acute renal failure. His serum creatinine was up to…

Nidia Messias, MD
By Nidia Messias, MD
ANCA Disease, LECT2 Amyloid, IgG4-Related Disease, AL amyloidosis, ANCA, digging deeper, Dr. Messias, Arkana Laboratories, pathology diseases
Digging Deeper

Hidden Treasures

This biopsy came to us due to acute renal failure and proteinuria. The patient was a gentleman in his late…

Nidia Messias, MD
By Nidia Messias, MD
Approximately 25-30% of the patients with anti-GBM crescentic glomerulonephritis are ANCA positive
Twitter Poll

Twitter Poll (February 1, 2018)

ANSWER: C Approximately 25-30% of the patients with anti-GBM crescentic glomerulonephritis are ANCA positive, usually for MPO-ANCA.

Vanessa Moreno, MD
By Vanessa Moreno, MD

Crescentic Glomerulonephritis with IgA Deposits
Teaching Points

Crescentic Glomerulonephritis with IgA Deposits

This biopsy was taken from a 58-year-old male with no significant past medical history, who presents with gross hematuria, serum…

MEST-C, IgA with Crescents
Teaching Points

IgA with Crescents, MEST-C

This biopsy is from a young adult patient with IgA nephropathy (the immunofluorescence image in Fig. 2 shows 2+ mesangial…

Fraction of Glomeruli With Crescents
Twitter Poll

Twitter Poll (September 27, 2017)

B-The fraction of glomeruli w/ crescents is the sole discriminator between classes II through V. This system predicts the clinical…

Vanessa Moreno, MD
By Vanessa Moreno, MD