Search & Filter All Posts
All Articles
(14 Results)
Hereditary Amyloid Neuropathy
Elderly female with amyloid neuropathy of the sural nerve. Cross-sections of the left sural nerve prepared from formalin-fixed paraffin-embedded (FFPE)…
Diagnose This (August 2, 2021)
This biopsy is from a 61yo male with DM, CHF, CKD4, and an abnormal SPEP. UMOD IHC was negative. What…
ALECT2 Amyloidosis
The patient is a 75-year-old Hispanic male who presents with progressively worsening kidney function and a creatinine of 1.6 mg/dl…
Step By Step
The biopsy is from a 65 year-old female who presented with acute renal failure and elevated creatinine up to 1.9…
IgA nephropathy with something extra…
The biopsy is from a 61-year-old man with a history of intermittent microscopic hematuria for many years who presents with…
Pushing Glass (April 6, 2018)
A 75-year-old Hispanic male presents with a creatinine of 3. His creatinine has slowly been creeping up over the last…
Twitter Poll (March 21, 2018)
ANSWER: B AAPOAI Amyloidosis is the 2nd most common systemic hereditary amyloidosis which can be seen in kidney, liver, larynx,…
Twitter Poll (September 12, 2017)
Answer: C Amyloid fibrils typically measure 8-12 nm (answer C). The deposits seen in Immunotactoid glomerulopathy are composed by tubules…
AA Amyloid
This biopsy from a patient with massive proteinuria showed diffuse and near-global involvement of glomeruli by amorphous deposits (Fig. 1)…
Pushing Glass (July 25, 2017)
The patient is a 64-year-old female who presents with 4.5 grams of proteinuria, hematuria, and a creatinine of 1.5. She…
Congo Red Stain
The ability to detect amyloid deposits in human tissue is the critical first step in making a diagnosis of amyloidosis.…
LECT2
Photomicrographs show extensive interstitial and glomerular deposition of Congo red positive material that stains positive for LECT2. Despite being one…
