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Muscle Pain
Clinical History The patient is a 54-year-old man with lower extremity pain and edema, weakness and fever following a respiratory…

Case 2: A Crescentic Conundrum
The patient is a 75-year-old female with a history of hypertension who presents with acute kidney injury. Her serum creatinine…

Disintegrating Capillary Loop Riddled with Microperformations
This acellular scanning EM shows disintegrating capillary loop riddled with microperformations in a patient with crescentic glomerulonephritis. Photo credits to…

Twitter Poll (December 11, 2019)
Answer: D, All of the Above Anti-GBM disease presents with rapidly progressive glomerulonephritis (GN) with or without pulmonary hemorrhage. On…

Crescentic IgA nephropathy
Focal crescentic IgA nephropathy The patient is a 17-year-old white female who presents with 2.85 grams/24 hr proteinuria, microscopic hematuria,…

Diagnose This (August 20, 2018)
What is your presumed diagnosis in the absence of immunofluorescence and electron microscopy? …

Digging Deeper, Literally
This biopsy came from a 79-year-old patient. He had presented with acute renal failure. His serum creatinine was up to…

Diagnose This (June 18, 2018)
In the presence of a negative immunofluorescence panel, what is your diagnosis? …

Evaluating Eosin-Stained Frozen Section Slides Using Fluorescence Microscopy
As published decades ago by Bonsib et al. (see reference), fluorescence microscopy of eosin-stained frozen section slides can be a…