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Focal Lupus Nephritis, mesangial hypercellularity
Teaching Points

Class III Focal Lupus Nephritis

This 9-year-old female was recently evaluated for lymphoid malignancy due to weight loss and intermittent fevers. Following a negative workup…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD
Intimal Arteritis
Teaching Points

Intimal Arteritis

The image in Figure 1 shows mild intimal arteritis in an allograft biopsy from a patient who had undergone a…

Monoclonal Gammopathy of Renal Significance
Diagnose This!

Diagnose This! (June 5, 2017)

Whats your diagnosis?   …

By L. Nich Cossey, MD

Chronic Active Tubulointerstitial Nephritis
Teaching Points

Chronic Active Tubulointerstitial Nephritis

39 y/o male presents with acute kidney injury, creatinine 3.5 mg/dl. Bland urinalysis, serologic studies negative. Immunofluorescence study of the…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD
BK nephritis
Pushing Glass

Pushing Glass (May 30, 2017)

A 62-year-old Asian male with a past medical history significant for ESRD secondary to hypertension S/P renal transplant (9 months…

Teaching Points

Light Chain Cast Nephropathy

Immunofluorescence staining with kappa light chain and lambda light chain antibodies shows negative kappa in casts that are lambda positive…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD

Medullary Angiitis
Teaching Points

Medullary Angiitis

The attached photomicrographs show the classic histopathology of renal medullary angiitis, a lesion involving the vasa recta of the medulla.…

IgG4-Positive Plasma Cells
Teaching Points

IgG4

Renal parenchyma with florid interstitial fibrosis with thick bands of sclerosis expanding the interstitium and pushing the tubules apart on…

Dense deposit disease
Pushing Glass

Pushing Glass (May 16, 2017)

A 15-year-old boy had a kidney biopsy because of the persistent nephrotic syndrome. His medical history is significant for resolved…

By Md Shahrier Amin, MD

Atheroemboli
Teaching Points

Atheroemboli

A PAS section shows an atheroembolus occluding an artery (arrow) with an adjacent ischemic appearing glomerulus. Atheroemboli appear as slit-like…

Atheroemboli
Diagnose This!

Diagnose This! (May 8, 2017)

What is your diagnosis?   …

By L. Nich Cossey, MD
Oxalate Nephropathy
Teaching Points

Oxalate Nephropathy

This biopsy is from a patient with metabolic acidosis, a CPK of 8000 mg/dl a creatinine of 22 mg/dl on…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD

HIV-associated nephropathy (HIVAN)
Pushing Glass

Pushing Glass (May 2, 2017)

A 45 year-old African American man presented with pneumonia, colitis and acute kidney injury (serum creatinine- 6 mg/dL). What is…

By Dao-Fu Dai, MD
Postpartum Hemolytic Uremic Syndrome (HUS)
Teaching Points

Postpartum HUS

Postpartum hemolytic uremic syndrome This 22-year-old Caucasian female presented with acute renal failure and proteinuria five days after delivering her…

Necrotizing Vasculitis
Teaching Points

Necrotizing Vasculitis

Necrotizing Vasculitis as seen with Silver Methenamine Massons Trichrome (SMMT) stain on a renal biopsy. The immunofluorescence panel was negative…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD