Search & Filter All Posts
All Articles
(45 Results)
IgA Differential
IgA nephropathy is defined by IgA dominant or co-dominant deposits in glomeruli in the absence of systemic disease. Other diseases…
Proliferative Glomerulonephritis with Monoclonal IgG Deposits
This biopsy was performed on an 81-year-male, status post renal transplant, who presented with increased creatinine (2.3 mg/dl) and microscopic…
Alport IF
In patients suspected of having Alport syndrome, immunofluorescence staining can be used to detect abnormal expression of various alpha chains…
Fibronectin Glomerulopathy
A renal biopsy was performed in a 32-year-old female with microscopic hematuria and nephrotic range proteinuria of 4 grams per…
Diagnose This! (January 8, 2018)
The immunofluorescence image shown is of IgA. What is the most likely diagnosis and clinical history? …
Crescentic Glomerulonephritis with IgA Deposits
This biopsy was taken from a 58-year-old male with no significant past medical history, who presents with gross hematuria, serum…
Cholesterol Microemboli
Cholesterol emboli involving the kidney may manifest clinically as acute kidney injury, hematuria, proteinuria (both non-nephrotic and nephrotic range), and…
IgA with Crescents, MEST-C
This biopsy is from a young adult patient with IgA nephropathy (the immunofluorescence image in Fig. 2 shows 2+ mesangial…
Acute Post-Infectious Glomerulonephritis
These renal biopsy images are from an 8-year-old boy who experienced the abrupt onset of hypertension, lower extremity edema, gross…
Alport Syndrome
This biopsy from a 22-year-old Hispanic male with a history of hematuria, subnephrotic proteinuria, and chronic kidney disease shows essentially…
Diagnose This! (October 23, 2017)
This IF image is from a 22 y/o Asian male with hematuria. What immunoreactant does it represent and what is…
Alport Skin
The most common form of Alport syndrome shows an X-linked dominant inheritance pattern and is caused by mutations in the…
Twitter Poll (October 18, 2017)
Answer B is the best answer. Hematuria, while possible, is an uncommon presenting symptom of membranous glomerulopathy.
Fabry Disease and IgA
A 34-year-old Asian female underwent a renal biopsy as part of the workup for progressively worsening renal function (Cr =…
Thrombotic Microangiopathy
This biopsy is from a person in their 40s, who presented with accelerated hypertension and blood pressure of 240/180 mm/Hg.…
