Search & Filter All Posts
All Articles
(45 Results)![IgA, IgA Differential, IgA nephropathy](https://www.arkanalabs.com/wp-content/uploads/5386-iga04-432x288.jpg)
IgA Differential
IgA nephropathy is defined by IgA dominant or co-dominant deposits in glomeruli in the absence of systemic disease. Other diseases…
![mild endocapillary hypercellularity with rare double contour formation of the capillary loops, Proliferative Glomerulonephritis with Monoclonal IgG Deposits](https://www.arkanalabs.com/wp-content/uploads/Fig-1-copy-39-432x288.jpg)
Proliferative Glomerulonephritis with Monoclonal IgG Deposits
This biopsy was performed on an 81-year-male, status post renal transplant, who presented with increased creatinine (2.3 mg/dl) and microscopic…
![Alport Syndrome Detected with IF](https://www.arkanalabs.com/wp-content/uploads/Fig-1_Alport-staining-copy-432x288.jpg)
Alport IF
In patients suspected of having Alport syndrome, immunofluorescence staining can be used to detect abnormal expression of various alpha chains…
![extensive mesangial and subendothelial deposition of PAS-positive](https://www.arkanalabs.com/wp-content/uploads/A-2-432x288.jpg)
Fibronectin Glomerulopathy
A renal biopsy was performed in a 32-year-old female with microscopic hematuria and nephrotic range proteinuria of 4 grams per…
![IgA Nephropathy](https://www.arkanalabs.com/wp-content/uploads/8-Mesangial-IgA-IF-copy-1-432x288.jpg)
Diagnose This! (January 8, 2018)
The immunofluorescence image shown is of IgA. What is the most likely diagnosis and clinical history? …
![Crescentic Glomerulonephritis with IgA Deposits](https://www.arkanalabs.com/wp-content/uploads/Fig-1-copy-432x288.jpg)
Crescentic Glomerulonephritis with IgA Deposits
This biopsy was taken from a 58-year-old male with no significant past medical history, who presents with gross hematuria, serum…
![Cholesterol Microemboli](https://www.arkanalabs.com/wp-content/uploads/Fig-1_cholesterol-emoboli-copy-432x288.jpg)
Cholesterol Microemboli
Cholesterol emboli involving the kidney may manifest clinically as acute kidney injury, hematuria, proteinuria (both non-nephrotic and nephrotic range), and…
![MEST-C, IgA with Crescents](https://www.arkanalabs.com/wp-content/uploads/Fig-1_MEST-C-copy-1-432x288.jpg)
IgA with Crescents, MEST-C
This biopsy is from a young adult patient with IgA nephropathy (the immunofluorescence image in Fig. 2 shows 2+ mesangial…
![Acute Post-Infectious Glomerulonephritis](https://www.arkanalabs.com/wp-content/uploads/Fig-1_Acute-postinfectious-copy-1-432x288.jpg)
Acute Post-Infectious Glomerulonephritis
These renal biopsy images are from an 8-year-old boy who experienced the abrupt onset of hypertension, lower extremity edema, gross…
![Alport Syndrome](https://www.arkanalabs.com/wp-content/uploads/Figure-1-copy-4-432x288.jpg)
Alport Syndrome
This biopsy from a 22-year-old Hispanic male with a history of hematuria, subnephrotic proteinuria, and chronic kidney disease shows essentially…
![IgA nephropathy](https://www.arkanalabs.com/wp-content/uploads/Mesangial-IgA-Deposits-1-432x288.jpg)
Diagnose This! (October 23, 2017)
This IF image is from a 22 y/o Asian male with hematuria. What immunoreactant does it represent and what is…
![X-linked Alport syndrome](https://www.arkanalabs.com/wp-content/uploads/2-Alpha-2-copy-432x288.jpg)
Alport Skin
The most common form of Alport syndrome shows an X-linked dominant inheritance pattern and is caused by mutations in the…
![Hematuria](https://www.arkanalabs.com/wp-content/uploads/tp10.18-432x288.jpg)
Twitter Poll (October 18, 2017)
Answer B is the best answer. Hematuria, while possible, is an uncommon presenting symptom of membranous glomerulopathy.
![Fabry disease](https://www.arkanalabs.com/wp-content/uploads/Fig-1-copy-18-432x288.jpg)
Fabry Disease and IgA
A 34-year-old Asian female underwent a renal biopsy as part of the workup for progressively worsening renal function (Cr =…
![Thrombotic Microangiopathy](https://www.arkanalabs.com/wp-content/uploads/1-2-interstitial-fibrosis-copy-1-432x288.jpg)
Thrombotic Microangiopathy
This biopsy is from a person in their 40s, who presented with accelerated hypertension and blood pressure of 240/180 mm/Hg.…