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Chronic Lesions of ANCA – Fibrous Crescents
Fibrous crescents can be differentiated from ischemic obsolescent glomeruli based on the pattern of global sclerosis. The fibrous crescent has…
Hemoglobin Casts
This 58-year-old African American male without significant past medical history presents with fatigue and weakness. During workup, he was found…
Twitter Poll (June 28, 2018)
ANSWER: A This is true. In contrast, a diagnosis of combined class IV and class V lupus nephritis is warranted…
Twitter Poll (June 20, 2018)
ANSWER: D While the majority of cryoglobulinemic GNs do not show ultrastructural organization in deposits by EM, classically described deposits…
Diagnose This (June 18, 2018)
In the presence of a negative immunofluorescence panel, what is your diagnosis? …
Light Chain Proximal Tubulopathy Without Crystals Tutorial
The two most common morphologic variants of light chain proximal tubulopathy (LCPT) are LCPT with and without crystal formation. The…
Antiphospholipid Antibody Syndrome
This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for…
Granulomatous Interstitial Nephritis in CLL
This is a renal biopsy from a 62-year-old female with a recent diagnosis of CLL/SLL, who presents with rapidly worsening…
Diagnose This (June 11, 2018)
What is this finding and what is it classically associated with? …
Twitter Poll (May 30, 2018)
ANSWER: C The kidney is the most common organ affected by cholesterol emboli in about 75% of the cases, followed…
Bile Stained Calcium Oxalate Crystals
A renal biopsy was performed on this 75-year-old female who presented with acute liver failure, jaundice and acute renal failure…
Pushing Glass (May 25, 2017)
The patient is a 74 year-old female who presents with a sudden rise in creatinine to 5.0. A week ago…
Twitter Poll (May 23, 2018)
True! Histologic evidence of acute tissue injury in AABMR includes 1 or more of the following: microvascular inflammation (glomerulitis and/or…
2,8 DHA Crystalline Nephropathy
The renal biopsy shown here has crystals present within the tubular lumens and cytoplasm with a brownish appearance by H&E…