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(140 Results)
Freezing Artifact
Neuro Notes

Suboptimal Snap Freezing

This 50-year-old patient presented with a two year history of bilateral upper extremity muscle weakness. They also complained of muscle…

Russell Bodies on Gomori Trichrome Stain
Neuro Notes

Polymyositis With Plasma Cells

This 50-year-old patients muscle biopsy showed morphologic changes of polymyositis. Their past medical history is significant for rheumatoid arthritis. What…

Microfascicles
Neuro Notes

Toluidine Blue Stained Thick Section

This 75-year-old patient presented with complaints of numbness, tingling and burning sensation involving his right lower extremity below the level…


These changes shown on toluidine blue-stained thick section represent partial crush and/or traction artifact
Neuro Notes

Toluidine Blue Stained Thick Section

This 57-year-old patient presented with a left foot drop of several weeks duration. Laboratory studies showed elevated ESR, and negative/normal…

axon, Myelin incisure, Schmidt-Lanterman Incisure, myelin sheath
Neuro Notes

Schmidt-Lanterman Incisure

This 60-year-old patient presented with complaints of fatigue, lower back pain, and slowly progressive bilateral foot drop. Laboratory studies showed…

Diabetic, Neuropathy In A Diabetic Patient
Neuro Notes

Neuropathy In A Diabetic Patient

This patient presented with a multiple-year history of progressively worsening numbness and tingling which began in their feet and progressed…


IDH-Wildtype Glioblastoma
Neuro Notes

Unusual Brain Neoplasm

This 60-year-old patient presented with acute onset unilateral stroke-type symptoms. Imaging studies (brain CT and MRI) identified a left 5.0…

Fetal Brain
Neuro Notes

Fetal Brain

This image shows the brain of a twenty-six-week-old stillborn baby. What anatomic landmark is marked by the arrow in figure…

Neuro Notes

Unexpected Neuropathy

This 45-year-old previously healthy patient presented with a 4-year history of progressive numbness and dysesthesias involving their hands and feet…


Polyglucosan bodies, Some of the muscle fibers in this image contain multiple refractile angular/rhomboid shaped well-circumscribed structures within the sarcoplasm
Neuro Notes

Muscle Inclusions

This 50-year-old patient presented with complaints of progressive leg weakness and dysesthesia (burning sensation) in a sock and glove distribution.…

Vacuolar myopathy
Neuro Notes

Vacuolar Myopathy

This 50-year-old male presented with profound upper and lower extremity proximal muscle weakness. His family history was negative for neuromuscular…

Chordoid meningioma
Neuro Notes

Dural-Based Extra-Axial Mass

This 50-year-old patient presented with visual changes and word-finding difficulties. Brain MRI demonstrated a 4.6 x 4.5 x 3.5 cm…


B-cell Lymphoma
Neuro Notes

B-Cell Lymphoma Muscle Mass

This 70-year-old patient presented with generalized muscle weakness, weight loss, decreased appetite, mild hypercalcemia, and a 2-month history of progressive…

Neuro Notes

Congo Red Elastic Lamina

This previously healthy 30-year-old patient presented with tingling and numbness involving their extremities, followed by progressive lower extremity muscle weakness…

Neuro Notes

Perifascicular MHC1

This middle-aged patient presented with complaints of proximal muscle weakness, myalgias, and skin rash (face and chest) of several months…