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(29 Results)![Thrombotic microangiopathy](https://www.arkanalabs.com/wp-content/uploads/2022/08/Figure-1-5-432x288.jpg)
Diagnose This (August 22, 2022)
This is a 3 month post-transplant kidney biopsy from a patient with ESRD due to polycystic kidney disease. She recently…
![thrombotic microangiopathy](https://www.arkanalabs.com/wp-content/uploads/2022/04/Figure-1-600x600-1-432x288.jpg)
Diagnose This (January 10, 2022)
This is the H&E from the frozen tissue submitted for IF examined under fluorescent light. In a patient with anemia,…
![anti-brush border antibody disease, ABBA, renal pathology, Twitter Poll, arkana labs](https://www.arkanalabs.com/wp-content/uploads/12/23/Twitter-Poll-Template-432x288.jpg)
Twitter Poll (December 23, 2020)
Answer: D The histologic features of a thrombotic microangiopathy (TMA) are non-specific as to etiology and include both acute and…
![Thrombotic Microangiopathy](https://www.arkanalabs.com/wp-content/uploads/TMA-painting-copy-scaled-432x288.jpg)
Art of Medicine: Thrombotic Microangiopathy
The above painting shows a glomerulus containing capillary loop fibrin thrombi, an arteriole with onion-skinning, and acute tubular injury, findings…
KDIGO Connections: SLE and TMA
Remember to think about TMA lesions in your patients with lupus!
![Disease Week, onco-nephrology, cancer, nephropathology](https://www.arkanalabs.com/wp-content/uploads/09/10/Disease-Week-2021-Onconephrology-432x288.jpg)
Disease Week: Onco-Nephrology
Monday Onco-nephrology is a rapidly developing area of nephrology designed to help address and prevent kidney problems and the many…
KDIGO Connections: Atypical Hemolytic-Uremic Syndrome
How do you treat patients with atypical hemolytic-uremic syndrome? Learn more about treatment and atypical hemolytic-uremic syndrome through KDIGO Connections!…
![Acute kidney injury, anti-centromere antibodies, ischemia, schistoctes, scleroderma renal crisis, thrombotic microangiopathy, scleroderma](https://www.arkanalabs.com/wp-content/uploads/Figure-1-copy-14-432x288.jpg)
Scleroderma
The patient is a 32-year-old African American female who presents with hypertensive urgency, positive ANA, positive anti-RNA polymerase III antibody,…
![](https://www.arkanalabs.com/wp-content/uploads/TBT-with-Dr.-Fred-Silva-5-432x288.jpg)
Circumferential Mesangial Interposition
Mesangial cell interposition between GBMs is an unusual and not fully understood process. In this episode, Dr. Silva discusses where…
![Scleroderma in a renal biopsy at Arkana Laboratories](https://www.arkanalabs.com/wp-content/uploads/x26-copy-1-432x288.jpg)
Diagnose This (August 27, 2018)
What is this finding and what is the likely etiology? …
![TMA, TMA Lesions with Multiple Etiologies](https://www.arkanalabs.com/wp-content/uploads/tp2.28-9-432x288.jpg)
Twitter Poll (August 15, 2018)
ANSWER: D TMA is a lesion with multiple etiologies including HUS, TTP, STEC- HUS, complement dysregulation (atypical HUS), malignant HTN,…
![Thrombotic Microangiopathy](https://www.arkanalabs.com/wp-content/uploads/Fig-1-copy-56-432x288.jpg)
Endocapillary Hypercellularity in Thrombotic Microangiopathy
This renal biopsy performed on a 14-year-old boy shows changes diagnostic of a thrombotic microangiopathy (TMA). These changes include frequent…
![Anti-VEGF Effect](https://www.arkanalabs.com/wp-content/uploads/Fig-1_TMA-changes-in-VEGF-copy-432x288.jpg)
Anti-VEGF Effect
This biopsy was taken from an older adult man with acute kidney injury and non-nephrotic range proteinuria. His medical history…