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Case 3: A Chameleon in Green
Clinical presentation The patient is a 45-year-old male with a history of IV drug use, hepatitis C, and multiple skin…
Diagnose This (August 24, 2021)
This is the biopsy of a 32yo IV drug user who has nephrotic range proteinuria and MSSA bacteremia secondary to…
Diagnose This (December 7, 2020)
What would be your leading Dx and subtype based on the Congo red image above showing deposition predominately in the…
AL Amyloidosis
A 70 year-old female presents with nephrotic range proteinuria and a creatinine of 1.2. She was in her normal level…
Twitter Poll (January 30, 2019)
ANSWER: B The medulla is the only compartment affected by AAPOAIV amyloidosis, sometimes with large amounts of amyloid. Glomeruli and…
One little, two little, three little findings…
This biopsy came to us for evaluation of nephrotic syndrome. The patient is a Hispanic gentleman in his late 80s,…
LECT2 Amyloidosis
The renal biopsy from this 79-year-old Hispanic male shows extensive glomerular, tubulointerstitial and vascular deposition of a PAS-pale (Fig 1),…
Pushing Glass (April 6, 2018)
A 75-year-old Hispanic male presents with a creatinine of 3. His creatinine has slowly been creeping up over the last…
Congo Red Stain Tutorial
Congo Red Stain Tutorial: What does it show? Positive Congo red staining in tissue with apple-greenbirefringenceunderpolarized lightis diagnostic of the…
Fibrinogen Aα-chain Amyloidosis
A 65-year-old male, with no significant past medical history, presents with proteinuria and worsening renal function. The serum creatinine is…
Apolipoprotein A-IV Amyloidosis
This renal biopsy from a 71-year-old female, who presented with progressively worsening renal failure, shows unremarkable glomeruli by light microscopy…
Twitter Poll (September 12, 2017)
Answer: C Amyloid fibrils typically measure 8-12 nm (answer C). The deposits seen in Immunotactoid glomerulopathy are composed by tubules…
Pushing Glass (July 25, 2017)
The patient is a 64-year-old female who presents with 4.5 grams of proteinuria, hematuria, and a creatinine of 1.5. She…