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Diagnose This! (January 9, 2023)
This is the biopsy of a 45 yo with alcoholic cirrhosis, bacteremia, hematuria, proteinuria and AKI. IF shows IgA (3+),…
IgA Nephropathy
What is IgA nephropathy? IgA nephropathyis one of the most common causes of kidney disease. In IgA nephropathy, an abnormal…
Twitter Poll (April 9, 2020)
ANSWER: C In one of the largest cases series by Ambruz et al., IgA nephropathy (IgAN) was the most common…
IgA Dominant Infection-Associated Glomerulonephritis
A 65-year-old male presents to the ER with a new onset rash and blood in his urine. The ER doc…
Potential Diagnostic Pitfall of PIF Method
The paraffin immunofluorescence technique is simple to perform for renal pathology laboratories familiar with routine IF. It is important as…
Diagnose This! (January 8, 2018)
The immunofluorescence image shown is of IgA. What is the most likely diagnosis and clinical history? …
Crescentic Glomerulonephritis with IgA Deposits
This biopsy was taken from a 58-year-old male with no significant past medical history, who presents with gross hematuria, serum…
IgA with Crescents, MEST-C
This biopsy is from a young adult patient with IgA nephropathy (the immunofluorescence image in Fig. 2 shows 2+ mesangial…
Diagnose This! (October 23, 2017)
This IF image is from a 22 y/o Asian male with hematuria. What immunoreactant does it represent and what is…
IgAN and Acute Tubular Injury with Legionella
Acute kidney injury in the setting of Legionella pneumonia. This biopsy is a middle-aged person with Legionella pneumonia who developed…
IgA Nephropathy
Figure 1 shows a renal biopsy from a 29-year-old man with no significant past medical history, who was found to…