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Art of Medicine: Proliferative Glomerulonephritis
The above painting shows endocapillary hypercellularity with mononuclear cells and neutrophils, as well as hyaline deposits within glomeruli. Red blood…
Infection-Associated Glomerulonephritis
A 60-year-old male presents with a painful left hip, hematuria, and a creatinine of 1.5 mg/dl. He was recently hospitalized…
Infection-Associated Glomerulonephritis
This biopsy is taken from a 39-year-old woman who presents with abdominal pain, ascites, and lower extremity edema. Her serum…
Twitter Poll (July 26, 2018)
ANSWER: C The patient has a Diffuse Lupus Nephritis, Class IV-S (A). Although biopsy shows focal and segmental proliferative glomerulonephritis…
When Lightning Strikes Twice
This biopsy came to us for a workup on proteinuria. The patient is a 68-year-old female with a history of…
Pushing Glass (March 13, 2018)
A 65-year-old male presents with mild proteinuria and a sudden increase in creatinine. He was recently diagnosed with widely metastatic…
Membranoproliferative Glomerulonephritis Pattern
This glomerulus shows a membranoproliferative glomerulonephritis (MPGN) pattern of injury. To a large extent, the etiologic differential diagnosis depends on…
Twitter Poll (January 4, 2018)
ANSWER: D Endocapillary hypercellularity, crescents, karyorrhexis and wire loops are some of the glomerular lesions seen in lupus nephritis class…
Infection-Associated GN
This kidney biopsy was performed on a 63-year-old female with a history of hypertension, congestive heart failure, lower extremity edema…
Acute Post-Infectious Glomerulonephritis
These renal biopsy images are from an 8-year-old boy who experienced the abrupt onset of hypertension, lower extremity edema, gross…
Infective Endocarditis-Associated Glomerulonephritis
This renal biopsy was taken from a 35 year old male with history of intravenous drug abuse and MRSA tricuspid…
Trichrome Staining in Deposits
While the trichrome stain is best known for assessing the extent of interstitial fibrosis, it is a versatile stain with…
Proliferative Glomerulonephritis with Monoclonal IgG Deposits
This 76-year-old white female developed nephrotic syndrome over about 3 months. She has proteinuria, 9 gm/24h and an elevated creatinine…
