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Vasculitis with Fibrinoid Necrosis
Clinical History: History: 68-year-old man with 1 week of bilateral proximal upper and lower extremity weakness and 1 month of…
68-Year-Old Man with Weakness
Clinical History:History: 68-year-old man with 1 week of bilateral proximal upper and lower extremity weakness and 1 month of facial,…
Needle Core Biopsy Muscle
Clinical History:This 50-year-old patient presented with progressively worsening muscle weakness of one month duration. Their past medical history was significant…
Myasthenia-Inflammatory Myopathy (MG-IM)
Clinical History:This 60-year-old patient presented with complaints of worsening hand weakness (particularly finger extensors). The weakness initially involved the right…
Denervation with Incidental Vascular Amyloid
Clinical History:This 76-year-old male presented with complaints of muscle pain. Their past medical history is significant for Sjogren’s syndrome, fibromyalgia,…
Toxic Vacuolar Myopathy Due to Hydroxychloroquine
Clinical History:This 50-year-old patient presented with a one year history of of persistent muscle weakness. They also had shortness of…
Sporadic Late-Onset Nemaline Myopathy
Clinical History:The patient is a 69-year-old male who presented with complaints of proximal lower extremity muscle weakness and BMI of…
Lipid Storage Myopathy in 77-Year-Old Patient
Clinical History:The patient is a 77-year-old female with several months of progressive muscle weakness predominantly in her upper and lower…
Vasculitic Neuropathy
Clinical History:65-year-old woman with generalized weakness and fatigue requiring a walker.Past medical history: anemia, major depressive disorder, MCI, arthritis, CTS,…
Anti-TIF1-γ in Dermatomyositis
Clinical History:73-year-old man who presented with inability to rise from a chair.Past medical history: arthritis, hypertension and hypercholesterolemia, and male…
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Clinical History:The patient is a 65-year-old woman with progressive proximal and generalized weakness, dysphasia, full-body pain, fasciculations and malaise.Medication: IVIG…
Vasculitis: Using Fluorescence Microscopy to Visualize Elastic Lamina
Clinical History:This 65-year-old patient presented with a two-month history of progressive proximal upper and lower extremity muscle weakness, and photosensitive…
Collagen Pockets in Nerve Biopsy
Clinical History:This 40-year-old patient underwent sural nerve biopsy to evaluate for a painful mixed large fiber and small fiber axonal…
Denervated Neuromuscular Junctions
Clinical History:Muscle biopsy from this 40-year-old patient showed morphologic and enzyme histochemical features of denervation.What abnormality is seen in the…
Gallyas Stain: Plaques, Tangles, and Threads in Alzheimer’s Disease
Clinical History:Neuropathologic examination (brain autopsy) on this 65-year-old patient with a history of slowly progressive dementia demonstrated gross and microscopic…