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(213 Results)
Denervated Neuromuscular Junctions
Clinical History:Muscle biopsy from this 40-year-old patient showed morphologic and enzyme histochemical features of denervation.What abnormality is seen in the…
Gallyas Stain: Plaques, Tangles, and Threads in Alzheimer’s Disease
Clinical History:Neuropathologic examination (brain autopsy) on this 65-year-old patient with a history of slowly progressive dementia demonstrated gross and microscopic…
Myopathic changes on Alkaline phosphatase
Clinical History:This 40-year-old patient presented with complaints of muscle weakness and myalgias of approximately 3-months duration. Laboratory studies showed elevated…
Ring Fibers
Which genetic test is required to establish the diagnosis in this 59-year-old with distal muscle weakness, mild myotonia, and persistently…
Vacuolar myopathy in 92-year-old male
Clinical History:The patient is a 92-year-old-male and presented progressive muscle weakness that began in the left upper extremity and spread…
76-year-old with numbness
Clinical History:The patient has numerous complaints including weakness, myalgia, arthralgia, back pain radiating down bilateral legs, cramps and twitching, imbalance,…
Perineurial microcalcification
Clinical History:This 55-year-old patient presented with symmetrical numbness, tingling and burning sensation involving the bottom of their feet which slowly…
Hybrid myofibers
Clinical History: This previously healthy 35-year-old patient presented with proximal upper and lower extremity weakness and myalgias. Laboratory studies showed…
End-stage nerve
Clinical History:This 45-year-old patient underwent sural nerve biopsy to evaluate for potential etiologies of their progressive sensorimotor predominantly axonal polyneuropathy.…
Freezing artifact formalin-fixed tissue
Clinical History: This 50-year-old patient presented with generalized muscle weakness and elevated CPK levels. Muscle biopsy was performed to evaluate…
Lower extremity pain and swelling
Clinical History:The patient is a 47-year-old man who presents with lower extremity swelling and pain x 5 days.Past medical history:…
76-year-old with weakness
Clinical History:The patient has numerous complaints including weakness, myalgia, arthralgia, back pain radiating down bilateral legs, cramps and twitching, imbalance,…
36-year-old man with longstanding weakness
Clinical History: Chief complaint: Weakness first presenting in teens. Family history: Brother with myopathy. Medication: Denies statins. Physical exam: Moderate…
71-year-old man with proximal weakness
Clinical History: Past medical history: advanced esophageal adenocarcinoma status post radiation and chemo/immunotherapy with immune mediated hepatitis, and moderate alcohol…
Neuromuscular junction in 60-year-old patient
Clinical History:Muscle biopsy was performed on this 60-year-old patient to evaluate for subjective complaints of muscle weakness. Several small intramuscular…