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Congo Red Elastic Lamina
This previously healthy 30-year-old patient presented with tingling and numbness involving their extremities, followed by progressive lower extremity muscle weakness…
Hereditary Amyloid Neuropathy
Elderly female with amyloid neuropathy of the sural nerve. Cross-sections of the left sural nerve prepared from formalin-fixed paraffin-embedded (FFPE)…
Diagnose This (August 2, 2021)
This biopsy is from a 61yo male with DM, CHF, CKD4, and an abnormal SPEP. UMOD IHC was negative. What…
ALECT2 Amyloidosis
The patient is a 75-year-old Hispanic male who presents with progressively worsening kidney function and a creatinine of 1.6 mg/dl…
Step By Step
The biopsy is from a 65 year-old female who presented with acute renal failure and elevated creatinine up to 1.9…
IgA nephropathy with something extra…
The biopsy is from a 61-year-old man with a history of intermittent microscopic hematuria for many years who presents with…
Vascular-Limited AL Amyloidosis
A renal biopsy was performed on this 78 year old male with history of diabetes mellitus, hypertension and monoclonal gammopathy…
Light Chain Cast Nephropathy with Congo Red Staining
This biopsy was taken from a 60-year-old African American female with a history of diabetes mellitus and hypertension, who presented…
Pushing Glass (April 6, 2018)
A 75-year-old Hispanic male presents with a creatinine of 3. His creatinine has slowly been creeping up over the last…
Congo Red Stain Tutorial
Congo Red Stain Tutorial: What does it show? Positive Congo red staining in tissue with apple-green birefringence under polarized light…
Fibrinogen Aα-chain Amyloidosis
A 65-year-old male, with no significant past medical history, presents with proteinuria and worsening renal function. The serum creatinine is…
Apolipoprotein A-IV Amyloidosis
This renal biopsy from a 71-year-old female, who presented with progressively worsening renal failure, shows unremarkable glomeruli by light microscopy…
Pushing Glass (August 8, 2017)
A 69-year-old man with past medical history of hypertension presents with nephrotic syndrome and 7 gm/day proteinuria. Serological studies are…
