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renal hemosiderosis, arkana laboratories, teaching point, renal pathology
Teaching Points

Hemosiderosis

An 80-year-old white male presents with a creatinine of 4.2 (baseline 1.1) on routine lab examination. His medical history is…

Lupus Nephritis, arkana laboratories, teaching point, nephropathology
Teaching Points

Lupus Nephritis (Class IV)

A 20-year-old female presents with hematuria, proteinuria, and a creatinine of 1.2 mg/dl. Serologies for ANA are positive. Complement levels…

Renal oxalosis, arkana laboratories, teaching point at arkana Laboratories, renal pathology
Teaching Points

Renal Oxalosis

A 25-year-old female presents to the hospital with malaise and a creatinine of 3.5. She reports that she was in…


Minimal Change Disease, teaching point, arkana laboratories, renal pathology
Teaching Points

Minimal Change Disease

A 70-year-old female presents with nephrotic range proteinuria.She had been in her regular state of health until 2 weeks ago…

Anti-GBM, renal pathology , diagnose this!, arkana laboratories
Diagnose This!

Diagnose This (January 21, 2019)

A limited sample showed this lesion and negative staining on paraffin-retrieved IF tissue. What is your diagnosis? …

By L. Nich Cossey, MD
ANCA Disease, LECT2 Amyloid, IgG4-Related Disease, AL amyloidosis, ANCA, digging deeper, Dr. Messias, Arkana Laboratories, pathology diseases
Digging Deeper

Digging Deeper – Here, There, and Everywhere

This biopsy came from an elderly gentleman in his 80s, who presented with acute renal failure. His serum creatinine had…

By Nidia Messias, MD

Infection-Associated Glomerulonephritis
Teaching Points

Infection-Associated Glomerulonephritis

A 60-year-old male presents with a painful left hip, hematuria, and a creatinine of 1.5 mg/dl. He was recently hospitalized…

IgA Dominant Infection-Associated Glomerulonephritis, renal pathology
Teaching Points

IgA Dominant Infection-Associated Glomerulonephritis

A 65-year-old male presents to the ER with a new onset rash and blood in his urine. The ER doc…

IgA, IgA Dominant Infection-Associated Glomerulonephritis, renal pathology, arkana laboratories, pathology of the kidney
Diagnose This!

Diagnose This (December 10, 2018)

What is your diagnosis?       The images show a necrotizing, crescentic, and endocapillary proliferative glomerulonephritis with IgA deposition…

By L. Nich Cossey, MD

surgical manipulation, pushing glass, arkana laboratories
Pushing Glass

Pushing Glass (December 7, 2018)

The patient is a 50-year-old female who presents 2 days after a renal transplant with a delay in graft function…

endocarditis-associated glomerulonephritis in renal biopsy at Arkana Laboratories
Diagnose This!

Diagnose This (December 3, 2018)

What is your diagnosis? What would you want to confirm your diagnosis?       …

By L. Nich Cossey, MD
PAS negative intratubular casts in renal biopsy at Arkana Laboratories
Diagnose This!

Diagnose This (November 12, 2018)

What is your diagnosis and what do you need to prove it?       …

By L. Nich Cossey, MD

Drug-induced AIN, Twitter Poll, Arkana Laboratories
Twitter Poll

Twitter Poll (November 1, 2018)

ANSWER: D Drug-induced AIN may account for 60-70% of AIN cases. Some offending drugs include: antibiotics, proton pump inhibitors, NSAIDs,…

By Vanessa Moreno, MD
Polyomavirus Nephropathy in Native Kidney
Teaching Points

Polyomavirus Nephropathy in Native Kidney

Polyomavirus nephropathy (PVN), predominantly caused by BK virus reactivation in the urogenital tract, is an important complication of renal allografts…

Fungus Microabscess, acute kidney disease
Teaching Points

Fungus Microabscess

Cortical microabscess formation is a clue to the presence of an infectious organism. Various bacteria, viruses, fungi, and even parasites…